Breast Cancer and Metals: A Literature Review
نویسندگان
چکیده
.....................................................................................................................4 Introduction/Background............................................................................................... 5 Developmental Nature of Breast Cancer...........................................................................6 Sources of Metals...................................................................................................... 7 How Metals Enter the Cell........................................................................................ 8 Effects of Metals in Enzyme Function........................................................................ 8 Genotoxic Effects of Metals in the Cell........................................................................ 9 Metals and Oxidative Stress....................................................................................... 9 Metals and Estrogen Receptors.................................................................................. 10 Metals and Tumor Suppressor Genes........................................................................... 10 Metals and Breast Cancer........................................................................................ 11 Arsenic...................................................................................................... 11 Cadmium................................................................................................... 13 Chromium................................................................................................ 15 Iron........................................................................................................ 17 Lead....................................................................................................... 18 Nickel....................................................................................................... 20 Zinc........................................................................................................ 21 The way forward.................................................................................................... 22 References.................................................................................................. 24 Table.................................................................................................................. 34
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